首 页機構概況機構設置科研人才隊伍合作交流研究生教育博士後圖書館創新文化黨群園地院重點實驗室彭桓武中心信息公開
  學術活動
  您現在的位置:首頁 > 學術活動 > 專題學術報告/Seminar
(Seminar) Mechanics of endocytosis under large osmotic pressure
2019-07-16  【 】【打印】【關閉

CAS Key Laboratory of Theoretical Physics

Institute of Theoretical Physics

Chinese Academy of Sciences

Seminar

Title

題目

Mechanics of endocytosis under large osmotic pressure

Speaker

報告人

马 锐

Affiliation

所在單位

Department of Molecular Biophysics and Biochemistry,Yale University

Date

日期

2019年7月16日(周二)下午3:00

Venue

地點

ITP South Building 6520

Abstract

摘要

In this talk, I will discuss membrane deformations powered by a point force under the condition of high pressure and low tension, which is rarely studied but directly relevant for endocytosis in yeast cells with a cell wall. I will show that the force-height relationship of membrane deformations under this condition is drastically different from that under conditions of high tension and low pressure. In addition, the boundary conditions at the attachment points of the membrane with the cell wall have dramatic effects on the force-height relationship. In particular, if the membrane is allowed to freely rotate at the attachment points, proteins that induced membrane curvature can lift the membrane off the cell wall without any external forces. This result is in sharp contrast with the conclusion of a previous study which adopted boundary conditions that fix the angle between the membrane and the cell wall at the attachment points. I will also discuss possible ways to pull the membrane off the cell wall against the high osmotic pressure with a small amount of force that can be provided by actin polymerization. 

Contact Person

所內聯系人

歐陽鍾燦
IE6.0浏览器,1024X768分辨率 博利彩票官网网址:http://www.aclcosm.com ? 博利彩票官网
地址:北京市海澱區中關村東路55號 郵政編碼:100190
京ICP備05002865號】 京公网安备1101080094号